To look at later to help with using MonoDevelop to make Mac apps:

Transitioning from Xcode 3 to Xcode 4 - Xamarin:

Introduction to Interface Builder v4.0

Although Interface Builder is now integrated into Xcode, itโ€™s still largely the same, with the exception of how Outlets and Actions are now created and wired up. Specifically, it gives you the ability to create an Outlet or an Action and wire it up to a control all in one step.

 If you believe what you're told, though the above link is for MonoTouch, MonoMac is similar.

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